InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0260) (VK646020)

Name: InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0260)
Brand: abinScience
SKU: VK646020
Price: 370 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

100ug
1mg

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK646020

Description

InVivoMAb Anti-Hantaan virus Glycoprotein C/Gc Broad-Neutralizing Antibody (Iv0260) [Iv0260] (VK646020) is a human monoclonal antibody detecting Envelopment polyprotein in ELISA, Neutralization. Suitable for Seoul virus (SEOV) and Andes virus (ANDV).

Species reactivity

Hantaan virus (HTNV), Puumala virus (PUUV), Dobrava-Belgrade virus (DOBV), Seoul virus (SEOV), Andes virus (ANDV), Sin Nombre virus (SNV)

Applications

ELISA, Neutralization

Host species

Human

Isotype

IgG1

Clone ID

Iv0260

Clonality

Monoclonal

Target

Envelopment polyprotein, M polyprotein, Glycoprotein C, Gc, Glycoprotein G2, GP

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q89905

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (Glycoprotein C/Gc) is a ~125 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3 (Probable). This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. May dysregulate normal immune and endothelial cell responses through an ITAM motif.

Note

For research use only. Not suitable for clinical or therapeutic use.

Images