InVivoMAb Anti-HCMV gB-neutralizing Antibody (SM5-1) (VK665010)

Name: InVivoMAb Anti-HCMV gB-neutralizing Antibody (SM5-1)
Brand: abinScience
SKU: VK665010
Price: 370 USD
Availability: InStock

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100ug
1mg

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Numéro de catalogue	VK665010
Description	InVivoMAb Anti-HCMV gB-neutralizing Antibody (SM5-1) [SM5-1] (VK665010) is a human monoclonal antibody detecting Envelope glycoprotein B in Neutralization.
Reactivité des espèces	Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5)
Applications	Neutralization
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1, lambda
ID de clone	SM5-1
Cible	Envelope glycoprotein B, gB, gB, UL55
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Produits associés	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P13201
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Envelope glycoprotein B (gB) is a ~101 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Note	For research use only. Not suitable for clinical or therapeutic use.