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InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2) (VK665030)

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InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)

InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)

InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)

InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)

InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)

InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)

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Spec:

100ug
1mg

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Overview
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References
Datasheet

Overview

Catalog No.	VK665030
Description	InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2) [1G2] (VK665030) is a human monoclonal antibody detecting Envelope glycoprotein B in ELISA, Neutralization.
Species reactivity	Human cytomegalovirus (strain Towne) (HHV-5) (Human herpesvirus 5)
Applications	ELISA, Neutralization
Host species	Human
Isotype	IgG1, kappa
Clone ID	1G2
Clonality	Monoclonal
Target	Envelope glycoprotein B, gB, gB, UL55
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P13201
RRID	InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2) (abinScience Cat# VK665030, RRID:AB_3729517)
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Envelope glycoprotein B (gB) is a ~101 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)
Bioactivity

Detects recombinant HCMV/HHV5 Envelope glycoprotein B/gB (Catalog No: VK665011) in indirect ELISA
Western blot

Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant HCMV/HHV5 Envelope glycoprotein B/gB(Catalog No: VK665011)
Lane 2: negative control
Lane 3: negative control

References

Datasheet

InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2).pdf

Formula

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InVivoMAb Anti-HCMV/HHV5 gB Neutralizing Antibody (1G2)