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| カタログ番号 | VK665010 |
|---|---|
| 説明 |
InVivoMAb Anti-HCMV gB-neutralizing Antibody (SM5-1) [SM5-1] (VK665010) is a human monoclonal antibody detecting Envelope glycoprotein B in Neutralization.
|
| 種反応性 | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) |
| アプリケーション | Neutralization |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, lambda |
| クローンID | SM5-1 |
| ターゲット | Envelope glycoprotein B, gB, gB, UL55 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P13201 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Envelope glycoprotein B (gB) is a ~101 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-HCMV gB-neutralizing Antibody (SM5-1)
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