

| Каталожный номер | VK665010 |
|---|---|
| Описание |
InVivoMAb Anti-HCMV gB-neutralizing Antibody (SM5-1) [SM5-1] (VK665010) is a human monoclonal antibody detecting Envelope glycoprotein B in Neutralization.
|
| Реактивность видов | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) |
| Применения | Neutralization |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG1, lambda |
| ID клона | SM5-1 |
| Цель | Envelope glycoprotein B, gB, gB, UL55 |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Связанные продукты | pH 7.4 Dilution Buffer |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | P13201 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Envelope glycoprotein B (gB) is a ~101 kDa protein. Envelope glycoprotein that plays a role in host cell entry, cell to-cell virus transmission, and fusion of infected cells. May be involved in the initial attachment via binding to heparan sulfate together with the gM/gN complex that binds heparin with higher affinity. Interacts with host integrin ITGB1, PDGFRA and EGFR that likely serve as postattachment entry receptors. Also participates in the fusion of viral and cellular membranes leading to virus entry into the host cell. Membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-HCMV gB-neutralizing Antibody (SM5-1)



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