

| Numéro de catalogue | VK705010 |
|---|---|
| Description |
InVivoMAb Anti-HCMV/HHV5 gH/UL75 Antibody (Iv0180) [Iv0180] (VK705010) is a human monoclonal antibody detecting Envelope glycoprotein H in ELISA, Neutralization.
|
| Reactivité des espèces | Human adenovirus C serotype 5 (HAdV-5) (Human adenovirus 5) |
| Applications | ELISA, Neutralization |
| Espèce hôte | Human |
| Clonalité | Monoclonal |
| Isotype | IgG1, kappa |
| ID de clone | Iv0180 |
| Cible | Envelope glycoprotein H, gH, gH, UL75 |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >95% as determined by SDS-PAGE. |
| Produits associés | pH 7.4 Dilution Buffer |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | P12824 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Contexte | Envelope glycoprotein H (gH/UL75) is a ~84 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. In human cytomegalovirus, forms two distinct complexes to mediate viral entry, a trimer and a pentamer at the surface of the virion envelope. The gH-gL-gO trimer is required for infection in fibroblasts by interacting with host PDGFRA, and in glioblastoma cells by interacting with host EPHA2. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-HCMV/HHV5 gH/UL75 Antibody (Iv0180).




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