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| カタログ番号 | VK681070 |
|---|---|
| 説明 |
InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A) [AR4A] (VK681070) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
|
| 種反応性 | Hepatitis C Virus (HCV) |
| アプリケーション | ELISA, Neutralization |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1 |
| クローンID | AR4A |
| ターゲット | Envelope glycoprotein E1, gp32, gp35, Envelope glycoprotein E2, NS1, gp68, gp70 |
| エンドトキシンレベル | < 1 EU/mg |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P27958 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Genome polyprotein (E1 & E2 (gp35 & gp70)) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802 2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612 3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025 4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511 5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
SDS-PAGE for InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR4A)
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