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InVivoMAb Anti-HCV Envelope glycoprotein E2 Antibody (HC84.22) (VK681030)

InVivoMAb Anti-HCV Envelope glycoprotein E2 Antibody (HC84.22)
InVivoMAb Anti-HCV Envelope glycoprotein E2 Antibody (HC84.22)
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  • 100ug
  • 1mg
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  • SDS

Aperçu
Numéro de catalogueVK681030
Description
InVivoMAb Anti-HCV NS1/gp68/gp70/E2 Antibody (HC84.22) [HC84.22] (VK681030) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
Reactivité des espècesHepatitis C Virus (HCV)
ApplicationsELISA, Neutralization
Espèce hôteHuman
ClonalitéMonoclonal
IsotypeIgG1
ID de cloneHC84.22
Cible Envelope glycoprotein E2, NS1, gp68, gp70
Niveau d'endotoxines < 1 EU/mg
Pureté >95% as determined by SDS-PAGE.
Produits associés pH 7.4 Dilution Buffer
Purification Protein A/G purified from cell culture supernatant.
Numéro d'accès P27958
Forme Liquid
Tampon de stockage 0.01M PBS pH 7.4.

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Stabilité et stockage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte

Genome polyprotein (NS1/gp68) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable).

1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802
2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612
3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025
4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511
5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
Note For research use only. Not suitable for clinical or therapeutic use.
Images
  • InVivoMAb Anti-HCV Envelope glycoprotein E2 Antibody (HC84.22)

    SDS-PAGE

    SDS-PAGE for InVivoMAb Anti-HCV NS1/gp68/gp70/E2 Antibody (HC84.22)

Reférences
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
Recommandation

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