InVivoMAb Anti-HCV Envelope glycoprotein E2 Antibody (HC84.22) (VK681030)

Name: InVivoMAb Anti-HCV Envelope glycoprotein E2 Antibody (HC84.22)
Brand: abinScience
SKU: VK681030
Price: 370 USD
Availability: InStock

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100ug
1mg

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	VK681030
説明	InVivoMAb Anti-HCV NS1/gp68/gp70/E2 Antibody (HC84.22) [HC84.22] (VK681030) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
種反応性	Hepatitis C Virus (HCV)
アプリケーション	ELISA, Neutralization
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1
クローンID	HC84.22
ターゲット	Envelope glycoprotein E2, NS1, gp68, gp70
エンドトキシンレベル	< 1 EU/mg
純度	>95% as determined by SDS-PAGE.
関連製品	pH 7.4 Dilution Buffer
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	P27958
形態	Liquid
保存バッファー	0.01M PBS pH 7.4. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Genome polyprotein (NS1/gp68) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802 2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612 3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025 4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511 5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
注意事項	For research use only. Not suitable for clinical or therapeutic use.