InVivoMAb Anti-Human Thrombopoietin R/Tpo R Antibody (3D9) (HW601010)

Name: InVivoMAb Anti-Human Thrombopoietin R/Tpo R Antibody (3D9)
Brand: abinScience
SKU: HW601010
Price: 370 USD
Availability: InStock

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Prix(USD) :

Spécification :

100ug
1mg

Nombre :

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Aperçu
Images
Reférences
Fiche technique
SDS

Aperçu

Numéro de catalogue

HW601010

Description

InVivoMAb Anti-Human CD110/TPOR Antibody (3D9) [3D9] (HW601010) is a human monoclonal antibody detecting TPO-R in Agonist, ELISA. Suitable for Human.

Reactivité des espèces

Human

Applications

Agonist, ELISA

Espèce hôte

Human

Clonalité

Monoclonal

Isotype

IgG1

ID de clone

3D9

Cible

TPO-R, TPOR, Thrombopoietin receptor, MPL, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110

Niveau d'endotoxines

Please contact with the lab for this information.

Pureté

>95% as determined by SDS-PAGE.

Produits associés

pH 7.4 Dilution Buffer

Purification

Protein A/G purified from cell culture supernatant.

Numéro d'accès

P40238

Forme

Liquid

Tampon de stockage

0.01M PBS pH 7.4

Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.

Reconstitution

Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.

Informations d'utilisation du produit

Application	Dilution
ELISA	1:2000-1:20000

Stabilité et stockage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Contexte

Thrombopoietin receptor (CD110/TPOR) is a ~71 kDa protein. Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation. Upon activation by THPO, induces rapid tyrosine phosphorylation and activation of JAK2, providing docking sites for many signaling proteins such as STAT5, SHIP/INPP5D, GRB2, SOS1 and PI3K. In turn, These signaling cascades lead to the proliferation, survival, and differentiation of megakaryocytes, ultimately leading to increased platelet production.

1. Royer, Y. et al. (2005) The Journal of biological chemistry 280, 27251-61. PMID: 15899890

2. Tsutsumi, N. et al. (2023) Cell 186, 4189-4203.e22. PMID: 37633268

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Human CD110/TPOR Antibody (3D9)

Reférences

Fiche technique

InVivoMAb Anti-Human Thrombopoietin R/Tpo R Antibody (3D9).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Protéines Recombinantes

Anticorps

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