

| Número de catálogo | HB984010 |
|---|---|
| Descripción |
InVivoMAb Anti-Human CD9 Antibody (Iv0274) [Iv0274] (HB984010) is a human monoclonal antibody detecting Motility-related protein in ELISA, FuncS. Suitable for Human.
|
| Reactividad de especies | Human |
| Aplicaciones | ELISA, FuncS |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | Iv0274 |
| Objetivo | Motility-related protein, Leukocyte antigen MIC3, TSPAN29, Cell growth-inhibiting gene 2 protein, CD9, MIC3, p24, Tspan-29, MRP-1, 5H9 antigen, Tetraspanin-29, CD9 antigen |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Productos asociados | pH 7.4 Dilution Buffer |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P21926 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Fondo | CD9 antigen is a ~25 kDa protein. Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion. Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion. In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration. In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles. Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption. 1. Higginbottom, A. et al. (2003) Biochemical and biophysical research communications 311, 208-14. PMID: 14575715 2. Nakazawa, Y. et al. (2008) Blood 112, 1730-9. PMID: 18541721 3. Ikeyama, S. et al. (1993) The Journal of experimental medicine 177, 1231-7. PMID: 8478605 4. Takeda, Y. et al. (2003) The Journal of cell biology 161, 945-56. PMID: 12796480 5. Masellis-Smith, A. et al. (1994) Journal of immunology (Baltimore, Md. : 1950) 152, 2768-77. PMID: 7511626 |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SDS-PAGE for InVivoMAb Anti-Human CD9 Antibody (Iv0274)




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