

| Numéro de catalogue | HY377010 |
|---|---|
| Description |
InVivoMAb Anti-Human ENT2/SLC29A2 Antibody (Iv0157) [Iv0157] (HY377010) is a human monoclonal antibody detecting Equilibrative nitrobenzylmercaptopurine riboside-insensit... in ELISA, Neutralization. Suitable for Human.
|
| Reactivité des espèces | Human |
| Applications | ELISA, Neutralization |
| Espèce hôte | Human |
| Clonalité | Monoclonal |
| Isotype | IgG1, kappa |
| ID de clone | Iv0157 |
| Cible | Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, 36 kDa nucleolar protein HNP36, ENT2, Equilibrative nucleoside transporter 2, SLC29A2, Hydrophobic nucleolar protein, 36 kDa, Equilibrative NBMPR-insensitive nucleoside transporter, Nucleoside transporter, ei-type, Delayed-early response protein 12, Solute carrier family 29 member 2, HNP36, DER12 |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >95% as determined by SDS-PAGE. |
| Produits associés | pH 7.4 Dilution Buffer |
| Purification | Protein A/G purified from cell culture supernatant. |
| Numéro d'accès | Q14542 |
| Forme | Liquid |
| Tampon de stockage | 0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Contexte | Equilibrative nucleoside transporter 2 (ENT2/SLC29A2) is a ~50 kDa protein. Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent, passive transporter. Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine. Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites. 1. Ward, JL. et al. (2000) The Journal of biological chemistry 275, 8375-81. PMID: 10722669 2. Mangravite, LM. et al. (2003) American journal of physiology. Renal physiology 284, F902-10. PMID: 12527552 3. Ward, JL. et al. (2003) Archives of biochemistry and biophysics 411, 19-26. PMID: 12590919 4. Owen, RP. et al. (2006) Drug metabolism and disposition: the biological fate of chemicals 34, 12-5. PMID: 16214850 5. Yao, SY. et al. (2011) The Journal of biological chemistry 286, 32552-62. PMID: 21795683 6. Griffiths, M. et al. (1997) The Biochemical journal 328 ( Pt 3), 739-43. PMID: 9396714 7. Crawford, CR. et al. (1998) The Journal of biological chemistry 273, 5288-93. PMID: 9478986 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |

SDS-PAGE for InVivoMAb Anti-Human ENT2/SLC29A2 Antibody (Iv0157).
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