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| カタログ番号 | HY377010 |
|---|---|
| 説明 |
InVivoMAb Anti-Human ENT2/SLC29A2 Antibody (Iv0157) [Iv0157] (HY377010) is a human monoclonal antibody detecting Equilibrative nitrobenzylmercaptopurine riboside-insensit... in ELISA, Neutralization. Suitable for Human.
|
| 種反応性 | Human |
| アプリケーション | ELISA, Neutralization |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | Iv0157 |
| ターゲット | Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter, 36 kDa nucleolar protein HNP36, ENT2, Equilibrative nucleoside transporter 2, SLC29A2, Hydrophobic nucleolar protein, 36 kDa, Equilibrative NBMPR-insensitive nucleoside transporter, Nucleoside transporter, ei-type, Delayed-early response protein 12, Solute carrier family 29 member 2, HNP36, DER12 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q14542 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Equilibrative nucleoside transporter 2 (ENT2/SLC29A2) is a ~50 kDa protein. Bidirectional uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis. Functions as a Na(+)-independent, passive transporter. Involved in the transport of nucleosides such as inosine, adenosine, uridine, thymidine, cytidine and guanosine. Also able to transport purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil). Involved in nucleoside transport at basolateral membrane of kidney cells, allowing liver absorption of nucleoside metabolites. 1. Ward, JL. et al. (2000) The Journal of biological chemistry 275, 8375-81. PMID: 10722669 2. Mangravite, LM. et al. (2003) American journal of physiology. Renal physiology 284, F902-10. PMID: 12527552 3. Ward, JL. et al. (2003) Archives of biochemistry and biophysics 411, 19-26. PMID: 12590919 4. Owen, RP. et al. (2006) Drug metabolism and disposition: the biological fate of chemicals 34, 12-5. PMID: 16214850 5. Yao, SY. et al. (2011) The Journal of biological chemistry 286, 32552-62. PMID: 21795683 6. Griffiths, M. et al. (1997) The Biochemical journal 328 ( Pt 3), 739-43. PMID: 9396714 7. Crawford, CR. et al. (1998) The Journal of biological chemistry 273, 5288-93. PMID: 9478986 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG1 Recombinant Isotype Control Antibody (13R4) (HV080507) |
SDS-PAGE for InVivoMAb Anti-Human ENT2/SLC29A2 Antibody (Iv0157).
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