

| カタログ番号 | HV033010 |
|---|---|
| 説明 |
InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191) [Iv0191] (HV033010) is a human monoclonal antibody detecting High-temperature requirement A serine peptidase 1 in Blocking, ELISA. Suitable for Human.
|
| 種反応性 | Human |
| アプリケーション | Blocking, ELISA |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG2, kappa |
| クローンID | Iv0191 |
| ターゲット | High-temperature requirement A serine peptidase 1, Serine protease 11, HTRA1, PRSS11, HTRA, Serine protease HTRA1, L56 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | Q92743 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Serine protease HTRA1 (PRSS11) is a ~51 kDa protein. Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
| Isotype Control | Human IgG2 Recombinant Isotype Control Antibody (HyHEL-10) (HV988107) |

SDS-PAGE for InVivoMAb Anti-Human HTRA1/PRSS11 Antibody (Iv0191).


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