InVivoMAb Anti-Mouse TRANCE/TNFSF11/RANK L Antibody (7C6) (MT439010)

Name: InVivoMAb Anti-Mouse TRANCE/TNFSF11/RANK L Antibody (7C6)
Brand: abinScience
SKU: MT439010
Price: 370 USD
Availability: InStock

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Especificación:

100ug
1mg

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Vista general

Número de catálogo	MT439010
Descripción	InVivoMAb Anti-Mouse CD254/RANKL Antibody (7C6) [7C6] (MT439010) is a mouse monoclonal antibody detecting Tumor necrosis factor ligand superfamily member 11 in ELISA, Neutralization. Suitable for Mouse.
Reactividad de especies	Mouse
Aplicaciones	ELISA, Neutralization
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	VHH-mFc
ID de clon	7C6
Objetivo	Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254, Tumor necrosis factor ligand superfamily member 11, membrane form, Tumor necrosis factor ligand superfamily member 11, soluble form, Tnfsf11, Opgl, Rankl, Trance
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Productos asociados	pH 7.4 Dilution Buffer
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	O35235
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Tumor necrosis factor ligand superfamily member 11 (CD254/RANKL) is a ~35 kDa protein. Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. CD254 is the therapeutic target of denosumab (Prolia). 1. Linares, GR. et al. (2012) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 27, 1553-65. PMID: 22437732 2. Mahoney, DJ. et al. (2008) The Journal of biological chemistry 283, 25952-62. PMID: 18586671 3. Tiedemann, K. et al. (2013) Journal of cell science 126, 4187-94. PMID: 24039232 4. Omata, Y. et al. (2016) PloS one 11, e0157992. PMID: 27336669 5. Kim, H. et al. (2013) Cell metabolism 17, 249-60. PMID: 23395171 6. Decker, CE. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 15654-9. PMID: 26644563
Nota	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	VHH mIgG2a Fc Recombinant Isotype Control Antibody (HyHEL-10) (MP167023)

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SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Mouse CD254/RANKL Antibody (7C6).

Referencias

Datasheet

InVivoMAb Anti-Mouse TRANCE/TNFSF11/RANK L Antibody (7C6).pdf

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Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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