InVivoMAb Anti-Mouse TRANCE/TNFSF11/RANK L Antibody (7C6) (MT439010)

Name: InVivoMAb Anti-Mouse TRANCE/TNFSF11/RANK L Antibody (7C6)
Brand: abinScience
SKU: MT439010
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
1mg

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Каталожный номер	MT439010
Описание	InVivoMAb Anti-Mouse CD254/RANKL Antibody (7C6) [7C6] (MT439010) is a mouse monoclonal antibody detecting Tumor necrosis factor ligand superfamily member 11 in ELISA, Neutralization. Suitable for Mouse.
Реактивность видов	Mouse
Применения	ELISA, Neutralization
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	VHH-mFc
ID клона	7C6
Цель	Tumor necrosis factor ligand superfamily member 11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, RANKL, TNF-related activation-induced cytokine, TRANCE, CD254, Tumor necrosis factor ligand superfamily member 11, membrane form, Tumor necrosis factor ligand superfamily member 11, soluble form, Tnfsf11, Opgl, Rankl, Trance
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Связанные продукты	pH 7.4 Dilution Buffer
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	O35235
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Tumor necrosis factor ligand superfamily member 11 (CD254/RANKL) is a ~35 kDa protein. Cytokine that binds to TNFRSF11B/OPG and to TNFRSF11A/RANK. Osteoclast differentiation and activation factor. Augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. May also play an important role in enhanced bone-resorption in humoral hypercalcemia of malignancy. CD254 is the therapeutic target of denosumab (Prolia). 1. Linares, GR. et al. (2012) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 27, 1553-65. PMID: 22437732 2. Mahoney, DJ. et al. (2008) The Journal of biological chemistry 283, 25952-62. PMID: 18586671 3. Tiedemann, K. et al. (2013) Journal of cell science 126, 4187-94. PMID: 24039232 4. Omata, Y. et al. (2016) PloS one 11, e0157992. PMID: 27336669 5. Kim, H. et al. (2013) Cell metabolism 17, 249-60. PMID: 23395171 6. Decker, CE. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 15654-9. PMID: 26644563
Примечание	For research use only. Not suitable for clinical or therapeutic use.
Isotype Control	VHH mIgG2a Fc Recombinant Isotype Control Antibody (HyHEL-10) (MP167023)

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SDS-PAGE for InVivoMAb Anti-Mouse CD254/RANKL Antibody (7C6).

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InVivoMAb Anti-Mouse TRANCE/TNFSF11/RANK L Antibody (7C6).pdf

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