InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7) (MY583010)

Name: InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7)
Brand: abinScience
SKU: MY583010
Price: 370 USD
Availability: InStock

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Precio(USD):

Especificación:

100ug
1mg

Número:

Contáctenos

Vista general
Imágenes
Referencias
Datasheet
SDS

Vista general

Número de catálogo

MY583010

Descripción

InVivoMAb Anti-Mouse IL6R (15A7) [15A7] (MY583010) is a rat monoclonal antibody detecting Interleukin-6 receptor subunit alpha in ELISA, FACS, Functional assay, Research in vivo. Suitable for Mouse.

Highlights

●Multi-Application — Validated across multiple applications.

Reactividad de especies

Mouse

Aplicaciones

ELISA, FCM, Functional assay, Research in vivo

Especie huésped

Rat

Clonalidad

Monoclonal

Isotipo

IgG2b, kappa

ID de clon

15A7

Objetivo

CD126, IL-6 receptor subunit alpha, IL-6R 1, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6R, Interleukin-6 receptor subunit alpha, Membrane glycoprotein 80, Soluble interleukin-6 receptor subunit alpha, gp80, sIL6R

Nivel de endotoxinas

< 1 EU/mg

Pureza

>95% as determined by SDS-PAGE.

Purificación

Protein A/G purified from cell culture supernatant.

Número de acceso

P22272

Forma

Liquid

Buffer de almacenamiento

0.01M PBS pH 7.4.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Información de uso del producto

Aplicación	Dilución
ELISA	1:2000-1:20000

Estabilidad y almacenamiento

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Fondo

Interleukin-6 receptor subunit alpha (IL6R) is a ~51 kDa protein. Part of the receptor for interleukin 6. Binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitate an association with IL6ST. Activation leads to the regulation of the immune response, acute-phase reactions and hematopoiesis. The interaction with membrane-bound IL6R and IL6ST stimulates 'classic signaling', the restricted expression of the IL6R limits classic IL6 signaling to only a few tissues such as the liver and some cells of the immune system.

1. Larsen, JV. et al. (2017) Molecular and cellular biology 37. PMID: 28265003

2. Kang, S. et al. (2019) Immunity 50, 1007-1023. PMID: 30995492

3. Spencer, S. et al. (2019) The Journal of experimental medicine 216, 1986-1998. PMID: 31235509

Nota

For research use only.

Imágenes

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Mouse IL6R (15A7)

Referencias

Datasheet

InVivoMAb Anti-Mouse IL-6R alpha/IL6R Antibody (15A7).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Proteínas Recombinantes

Anticuerpos

Kits de Ensayo