InVivoMAb Anti-Mouse SIRP alpha/CD172a Antibody (Iv0259) (MX892020)

Name: InVivoMAb Anti-Mouse SIRP alpha/CD172a Antibody (Iv0259)
Brand: abinScience
SKU: MX892020
Price: 370 USD
Availability: InStock

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Спецификация:

100ug
1mg

Количество:

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Каталожный номер	MX892020
Описание	InVivoMAb Anti-Mouse SIRPA Antibody (Iv0259) [Iv0259] (MX892020) is a mouse monoclonal antibody detecting Tyrosine-protein phosphatase non-receptor type substrate 1 in ELISA, Neutralization. Suitable for Mouse.
Реактивность видов	Mouse
Применения	ELISA, Neutralization
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	lgG1 (D265A)
ID клона	Iv0259
Цель	BIT, Bit, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172a, Inhibitory receptor SHPS-1, MFR, MYD1, Macrophage fusion receptor, MyD-1 antigen, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, SIRP, SIRPA, Signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, p84
Уровень эндотоксинов	< 1 EU/mg
Чистота	>95% as determined by SDS-PAGE.
Связанные продукты	pH 7.4 Dilution Buffer
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P97797
Форма	Liquid
Буфер хранения	0.01M PBS pH 7.4. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Фон	Tyrosine-protein phosphatase non-receptor type substrate 1 (CD172a/SIRPA) is a ~56 kDa protein. Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. 1. Nakaishi, A. et al. (2008) Journal of molecular biology 375, 650-60. PMID: 18045614 2. Sarute, N. et al. (2019) PLoS biology 17, e3000137. PMID: 30726215
Примечание	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE for InVivoMAb Anti-Mouse SIRPA Antibody (Iv0259)

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InVivoMAb Anti-Mouse SIRP alpha/CD172a Antibody (Iv0259).pdf

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