Anti-Mouse SIRP alpha/CD172a Recombinant Antibody (SAA0817) (MX892107)

Name: Anti-Mouse SIRP alpha/CD172a Recombinant Antibody (SAA0817)
Brand: abinScience
SKU: MX892107
Price: 191 USD
Availability: InStock

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Overview

Catalog No.	MX892107
Species reactivity	Mouse
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG1
Clone ID	SAA0817
Clonality	Monoclonal
Target	BIT, Signal-regulatory protein alpha-1, Brain Ig-like molecule with tyrosine-based activation motifs, MFR, SIRP, Sirp-alpha-1, Sirp-alpha-2, PTPNS1, SIRPA, SHP substrate 1, CD172 antigen-like family member A, Sirp-alpha-3, Inhibitory receptor SHPS-1, Signal-regulatory protein alpha-3, CD172a, Tyrosine-protein phosphatase non-receptor type substrate 1, MyD-1 antigen, Bit, SHPS-1, Macrophage fusion receptor, Signal-regulatory protein alpha-2, SHPS1, MYD1, p84
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P97797
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.09% Sodium azide. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Tyrosine-protein phosphatase non-receptor type substrate 1 (CD172a/SIRPA) is a ~56 kDa protein. Immunoglobulin-like cell surface receptor for CD47. Acts as a docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function. Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. 1. Nakaishi, A. et al. (2008) Journal of molecular biology 375, 650-60. PMID: 18045614 2. Sarute, N. et al. (2019) PLoS biology 17, e3000137. PMID: 30726215
Note	For research use only.

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SDS-PAGE for Anti-Mouse CD172a/SIRPA Antibody (SAA0817)

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Datasheet

Anti-Mouse SIRP alpha/CD172a Recombinant Antibody (SAA0817).pdf

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Anti-Mouse SIRP alpha/CD172a Recombinant Antibody (SAA0817) (MX892107)

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