InVivoMAb Anti-NiV/HeV Pre-Fusion Glycoprotein Antibody (2D3) (VK521040)

Name: InVivoMAb Anti-NiV/HeV Pre-Fusion Glycoprotein Antibody (2D3)
Brand: abinScience
SKU: VK521040
Price: 370 USD
Availability: InStock

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1mg

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Numéro de catalogue	VK521040
Description	InVivoMAb Anti-Nipah virus/NiV F/Fusion glycoprotein F0 Antibody (2D3) [2D3] (VK521040) is a human monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, Neutralization. Suitable for Nipah virus (NiV).
Reactivité des espèces	Nipah virus (NiV)
Applications	ELISA, Neutralization
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	IgG1
ID de clone	2D3
Cible	Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Produits associés	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	Q9IH63
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Fusion glycoprotein F0 is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.
Note	For research use only. Not suitable for clinical or therapeutic use.