Anti-HeV/NiV Pre-Fusion Glycoprotein Recombinant Antibody (mAb66) (VK521013)

Name: Anti-HeV/NiV Pre-Fusion Glycoprotein Recombinant Antibody (mAb66)
Brand: abinScience
SKU: VK521013
Price: 126 USD
Availability: InStock

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Overview

Catalog No.	VK521013
Description	Anti-HeV/NiV Pre-Fusion Glycoprotein Recombinant Antibody (mAb66) (VK521013) is a mouse monoclonal antibody detecting NiV Fusion Glycoprotein,HeV Fusion Glycoprotein,NiV Pre-Fusion Glycoprotein,HeV Pre-Fusion Glycoprotein in FCM, Neutralization. Suitable for Nipah virus (NiV). Highlights ●Affinity Purified — Minimal background and high purity for reliable results. ●Multi-Application — Validated across multiple applications.
Species reactivity	Nipah virus (NiV)
Applications	FCM, Neutralization
Host species	Mouse
Clonality	Monoclonal
Isotype	IgG2a, kappa
Clone ID	mAb66
Target	F, Fusion glycoprotein F0, Protein F
Endotoxin level	< 10 EU/mg as determined by LAL method.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q9IH63
RRID	Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (mAb66) (abinScience Cat# VK521013, RRID:AB_3725237)
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Fusion glycoprotein F0 is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.
Note	For research use only.

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Bioactivity

SEC-HPLC detection for Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (mAb66).
SDS-PAGE

SDS-PAGE for Anti-HeV/NiV F/Fusion glycoprotein F0 Antibody (mAb66).

References

Datasheet

Anti-HeV/NiV Pre-Fusion Glycoprotein Recombinant Antibody (mAb66).pdf

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Formula

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Recombinant Proteins

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Anti-HeV/NiV Pre-Fusion Glycoprotein Recombinant Antibody (mAb66) (VK521013)

Overview

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References

Datasheet

SDS