InVivoMAb Anti-NiV/HeV Pre-Fusion Glycoprotein Antibody (2B12) (VK521050)

Name: InVivoMAb Anti-NiV/HeV Pre-Fusion Glycoprotein Antibody (2B12)
Brand: abinScience
SKU: VK521050
Price: 370 USD
Availability: InStock

データシート製品共有情報コピー

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100ug
1mg

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	VK521050
説明	InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12) [2B12] (VK521050) is a human monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, Neutralization. Suitable for Nipah virus (NiV).
種反応性	Nipah virus (NiV)
アプリケーション	ELISA, Neutralization
宿主種	Human
クローン性	Monoclonal
アイソタイプ	IgG1
クローンID	2B12
ターゲット	Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F, Prefusion Protein
エンドトキシンレベル	Please contact with the lab for this information.
純度	>95% as determined by SDS-PAGE.
関連製品	pH 7.4 Dilution Buffer
精製	Protein A/G purified from cell culture supernatant.
アクセッション番号	Q9IH63
形態	Liquid
保存バッファー	0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
背景	Fusion glycoprotein F0 (Prefusion Protein) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.
注意事項	For research use only. Not suitable for clinical or therapeutic use.