

| Каталожный номер | VK521050 |
|---|---|
| Описание |
InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12) [2B12] (VK521050) is a human monoclonal antibody detecting Fusion glycoprotein F0 in ELISA, Neutralization. Suitable for Nipah virus (NiV).
|
| Реактивность видов | Nipah virus (NiV) |
| Применения | ELISA, Neutralization |
| Хозяинский вид | Human |
| Клоональность | Monoclonal |
| Изотип | IgG1 |
| ID клона | 2B12 |
| Цель | Fusion glycoprotein F0, Protein F, Fusion glycoprotein F2, Fusion glycoprotein F1, F, Prefusion Protein |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >95% as determined by SDS-PAGE. |
| Связанные продукты | pH 7.4 Dilution Buffer |
| Очистка | Protein A/G purified from cell culture supernatant. |
| Номер доступа | Q9IH63 |
| Форма | Liquid |
| Буфер хранения | 0.01M PBS pH 7.4 Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Фон | Fusion glycoprotein F0 (Prefusion Protein) is a ~60 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. |
| Примечание | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-Nipah virus/NiV Prefusion Protein Antibody (2B12).




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