InVivoMAb Anti-Poliovirus Capsid protein VP1 Antibody (19B) (VK557020)

Name: InVivoMAb Anti-Poliovirus Capsid protein VP1 Antibody (19B)
Brand: abinScience
SKU: VK557020
Price: 370 USD
Availability: InStock

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100ug
1mg

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Vista general

Número de catálogo	VK557020
Descripción	InVivoMAb Anti-Poliovirus Capsid protein VP1 (19B) [19B] (VK557020) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
Reactividad de especies	Poliovirus type 1 (PV1)
Aplicaciones	ELISA, Neutralization
Especie huésped	Human
Clonalidad	Monoclonal
Isotipo	VHH-hFc
ID de clon	19B
Objetivo	Genome polyprotein, Capsid protein VP1, Capsid protein VP2
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Productos asociados	pH 7.4 Dilution Buffer
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P03300
Forma	Liquid
Buffer de almacenamiento	0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Fondo	Genome polyprotein (Capsid protein VP1) is a ~246 kDa protein. Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host cell receptor PVR to provide virion attachment to target host epithelial cells. This attachment induces virion internalization predominantly through clathrin- and caveolin-independent endocytosis in Hela cells and through caveolin-mediated endocytosis in brain microvascular endothelial cells. 1. Hogle, JM. et al. (1985) Science (New York, N.Y.) 229, 1358-65. PMID: 2994218 2. Strauss, M. et al. (2013) Journal of virology 87, 3903-14. PMID: 23365424 3. Strauss, M. et al. (2015) Journal of virology 89, 4143-57. PMID: 25631086 4. Brandenburg, B. et al. (2007) PLoS biology 5, e183. PMID: 17622193 5. Coyne, CB. et al. (2007) The EMBO journal 26, 4016-28. PMID: 17717529 6. Bergelson, JM. (2008) Trends in microbiology 16, 44-7. PMID: 18191571
Nota	For research use only. Not suitable for clinical or therapeutic use.

Imágenes

SDS-PAGE

SDS-PAGE for InVivoMAb Anti-Poliovirus Capsid protein VP1 (19B)

Referencias

Datasheet

InVivoMAb Anti-Poliovirus Capsid protein VP1 Antibody (19B).pdf

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Formula

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