InVivoMAb Anti-Poliovirus Capsid protein VP1 Antibody (19B) (VK557020)

Name: InVivoMAb Anti-Poliovirus Capsid protein VP1 Antibody (19B)
Brand: abinScience
SKU: VK557020
Price: 370 USD
Availability: InStock

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100ug
1mg

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Numéro de catalogue	VK557020
Description	InVivoMAb Anti-Poliovirus Capsid protein VP1 (19B) [19B] (VK557020) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
Reactivité des espèces	Poliovirus type 1 (PV1)
Applications	ELISA, Neutralization
Espèce hôte	Human
Clonalité	Monoclonal
Isotype	VHH-hFc
ID de clone	19B
Cible	Genome polyprotein, Capsid protein VP1, Capsid protein VP2
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>95% as determined by SDS-PAGE.
Produits associés	pH 7.4 Dilution Buffer
Purification	Protein A/G purified from cell culture supernatant.
Numéro d'accès	P03300
Forme	Liquid
Tampon de stockage	0.01M PBS pH 7.4 Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Contexte	Genome polyprotein (Capsid protein VP1) is a ~246 kDa protein. Forms an icosahedral capsid of pseudo T=3 symmetry with capsid proteins VP2 and VP3. The capsid is 300 Angstroms in diameter, composed of 60 copies of each capsid protein and enclosing the viral positive strand RNA genome. Capsid protein VP1 mainly forms the vertices of the capsid. Capsid protein VP1 interacts with host cell receptor PVR to provide virion attachment to target host epithelial cells. This attachment induces virion internalization predominantly through clathrin- and caveolin-independent endocytosis in Hela cells and through caveolin-mediated endocytosis in brain microvascular endothelial cells. 1. Hogle, JM. et al. (1985) Science (New York, N.Y.) 229, 1358-65. PMID: 2994218 2. Strauss, M. et al. (2013) Journal of virology 87, 3903-14. PMID: 23365424 3. Strauss, M. et al. (2015) Journal of virology 89, 4143-57. PMID: 25631086 4. Brandenburg, B. et al. (2007) PLoS biology 5, e183. PMID: 17622193 5. Coyne, CB. et al. (2007) The EMBO journal 26, 4016-28. PMID: 17717529 6. Bergelson, JM. (2008) Trends in microbiology 16, 44-7. PMID: 18191571
Note	For research use only. Not suitable for clinical or therapeutic use.

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InVivoMAb Anti-Poliovirus Capsid protein VP1 Antibody (19B).pdf

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