



| Número de catálogo | VK805010 |
|---|---|
| Descripción |
InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009) [CR3009] (VK805010) is a human monoclonal antibody detecting Nucleoprotein in ELISA, FCM, IF, Neutralization. Suitable for SARS-CoV-2.
Highlights
|
| Reactividad de especies | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
| Aplicaciones | ELISA, FCM, IF, Neutralization |
| Especie huésped | Human |
| Clonalidad | Monoclonal |
| Isotipo | IgG1, kappa |
| ID de clon | CR3009 |
| Aplicaciones probadas | WB |
| Objetivo | Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N Protein, SARS-CoV-2 |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >95% as determined by SDS-PAGE. |
| Productos asociados | pH 7.4 Dilution Buffer |
| Purificación | Protein A/G purified from cell culture supernatant. |
| Número de acceso | P0DTC9 |
| Forma | Liquid |
| Buffer de almacenamiento | 0.01M PBS pH 7.4 Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Fondo | Nucleoprotein (NP) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions. 1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373 2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782 3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661 |
| Nota | For research use only. Not suitable for clinical or therapeutic use. |

Western blot analysis was performed using anti-nucleoprotein monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011)
Lane 2: negative control

Detects recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011) in indirect ELISA




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