Anti-N Protein Polyclonal Antibody (VK805014)

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

VK805014

Description

Anti-N Protein Polyclonal Antibody (VK805014) is a rabbit polyclonal antibody detecting N Protein in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

SARS-CoV-2 (2019-nCoV)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant SARS-CoV-2 N Protein (Met1-Ala419).

Target

Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N Protein

Purification

Purified by antigen affinity column.

Accession

P0DTC9

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Nucleoprotein (NP) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions.

1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373

2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782

3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661

Note

For research use only.

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