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| カタログ番号 | VK805010 |
|---|---|
| 説明 |
InVivoMAb Anti-SARS-CoV-2 NP/Nucleoprotein Antibody (CR3009) [CR3009] (VK805010) is a human monoclonal antibody detecting Nucleoprotein in ELISA, FCM, IF, Neutralization. Suitable for SARS-CoV-2.
Highlights
|
| 種反応性 | Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) |
| アプリケーション | ELISA, FCM, IF, Neutralization |
| 宿主種 | Human |
| クローン性 | Monoclonal |
| アイソタイプ | IgG1, kappa |
| クローンID | CR3009 |
| テスト済みアプリケーション | WB |
| ターゲット | Nucleoprotein, N, Nucleocapsid protein, NC, Protein N, N Protein, SARS-CoV-2 |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >95% as determined by SDS-PAGE. |
| 関連製品 | pH 7.4 Dilution Buffer |
| 精製 | Protein A/G purified from cell culture supernatant. |
| アクセッション番号 | P0DTC9 |
| 形態 | Liquid |
| 保存バッファー | 0.01M PBS pH 7.4 データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 背景 | Nucleoprotein (NP) is a ~45 kDa protein. Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Attenuates the stress granules formation by reducing host G3BP1 access to host mRNAs under stress conditions. 1. Dinesh, DC. et al. (2020) PLoS pathogens 16, e1009100. PMID: 33264373 2. Nabeel-Shah, S. et al. (2022) iScience 25, 103562. PMID: 34901782 3. Dolliver, SM. et al. (2022) PLoS pathogens 18, e1011041. PMID: 36534661 |
| 注意事項 | For research use only. Not suitable for clinical or therapeutic use. |
Western blot analysis was performed using anti-nucleoprotein monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011)
Lane 2: negative control
Detects recombinant SARS-CoV-2 nucleoprotein (Catalog No: VK805011) in indirect ELISA
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