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Mouse Anti-Human Kappa Chain Monoclonal Antibody, FITC (HB980415)

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概要
カタログ番号HB980415
説明
Mouse Anti-Human Kappa Chain Monoclonal Antibody, FITC (HB980415) is a mouse monoclonal antibody detecting Kappa chain in ELISA, IF, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●FITC Conjugated — Ready for direct detection without secondary antibody.
種反応性Human
アプリケーションELISA, IF, WB
宿主種Mouse
クローン性Monoclonal
アイソタイプIgG1
抱合FITC
免疫原 Nature Protein
ターゲット Second antibody, Second Ab, Mouse Anti-Human IgG, Kappa Chain Monoclonal Antibody, FITC
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
関連製品 Mouse IgG1 kappa Recombinant Isotype Control Antibody (HyHEL-10), FITC
精製 Protein A/G purified from cell culture supernatant.
形態 Liquid
保存バッファー 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

安定性と保存 Store at 4°C 12 months.
背景

Immunoglobulin kappa constant (Kappa Chain) is a ~11 kDa protein. Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain.

1. Schroeder, HW. et al. (2010) The Journal of allergy and clinical immunology 125, S41-52. PMID: 20176268
2. McHeyzer-Williams, M. et al. (2011) Nature reviews. Immunology 12, 24-34. PMID: 22158414
3. Teng, G. et al. (2007) Annual review of genetics 41, 107-20. PMID: 17576170
注意事項 For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.
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参考文献
Formula
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