Mouse Anti-Human PMEL17/ME20M Recombinant Antibody (17A9) (HW380107)

Name: Mouse Anti-Human PMEL17/ME20M Recombinant Antibody (17A9)
Brand: abinScience
SKU: HW380107
Price: 191 USD
Availability: InStock

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Vista general

Número de catálogo	HW380107
Marca	abinScience
Reactividad de especies	Human, Mouse, Rat, Monkey
Aplicaciones	ELISA, FCM, IHC
Especie huésped	Mouse
Clonalidad	Monoclonal
Isotipo	IgG2a, kappa
ID de clon	17A9
Objetivo	ME20M, Melanocyte protein PMEL, Silver locus protein homolog, Secreted melanoma-associated ME20 antigen, D12S53E, 95 kDa melanocyte-specific secreted glycoprotein, SILV, P100, Premelanosome protein, PMEL17, ME20S, PMEL, ME20-S, ME20-M, P26, P1, Melanocytes lineage-specific antigen GP100, Melanocyte protein Pmel 17, Melanoma-associated ME20 antigen
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>95% as determined by SDS-PAGE.
Purificación	Protein A/G purified from cell culture supernatant.
Número de acceso	P40967
Forma	Liquid
Buffer de almacenamiento	0.01M PBS, pH 7.4, 0.09% Sodium azide. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Fondo	Melanocyte protein PMEL (PMEL17/ME20M) is a ~70 kDa protein. Forms physiological amyloids that play a central role in melanosome morphogenesis and pigmentation. The maturation of unpigmented premelanosomes from stage I to II is marked by assembly of processed amyloidogenic fragments into parallel fibrillar sheets, which elongate the vesicle into a striated ellipsoidal shape. In pigmented stage III and IV melanosomes, the amyloid matrix serves as a platform where eumelanin precursors accumulate at high local concentrations for pigment formation. May prevent pigmentation-associated toxicity by sequestering toxic reaction intermediates of eumelanin biosynthesis pathway.
Nota	For research use only.

Imágenes

Western blot

Western blot analysis was performed using anti-PMEL monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human PMEL (Catalog No: HW380012)
Lane 2: negative control
Bioactivity

Detects recombinant human PMEL (Catalog No: HW380012) in indirect ELISA

Referencias

Datasheet

Mouse Anti-Human PMEL17/ME20M Recombinant Antibody (17A9).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Working Solution

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