Mouse Anti-Human PMEL17/ME20M Recombinant Antibody (17A9) (HW380107)

Name: Mouse Anti-Human PMEL17/ME20M Recombinant Antibody (17A9)
Brand: abinScience
SKU: HW380107
Price: 191 USD
Availability: InStock

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Каталожный номер	HW380107
Бренд	abinScience
Реактивность видов	Human, Mouse, Rat, Monkey
Применения	ELISA, FCM, IHC
Хозяинский вид	Mouse
Клоональность	Monoclonal
Изотип	IgG2a, kappa
ID клона	17A9
Цель	ME20M, Melanocyte protein PMEL, Silver locus protein homolog, Secreted melanoma-associated ME20 antigen, D12S53E, 95 kDa melanocyte-specific secreted glycoprotein, SILV, P100, Premelanosome protein, PMEL17, ME20S, PMEL, ME20-S, ME20-M, P26, P1, Melanocytes lineage-specific antigen GP100, Melanocyte protein Pmel 17, Melanoma-associated ME20 antigen
Уровень эндотоксинов	Please contact with the lab for this information.
Чистота	>95% as determined by SDS-PAGE.
Очистка	Protein A/G purified from cell culture supernatant.
Номер доступа	P40967
Форма	Liquid
Буфер хранения	0.01M PBS, pH 7.4, 0.09% Sodium azide. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии.
Устойчивость и хранение	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Фон	Melanocyte protein PMEL (PMEL17/ME20M) is a ~70 kDa protein. Forms physiological amyloids that play a central role in melanosome morphogenesis and pigmentation. The maturation of unpigmented premelanosomes from stage I to II is marked by assembly of processed amyloidogenic fragments into parallel fibrillar sheets, which elongate the vesicle into a striated ellipsoidal shape. In pigmented stage III and IV melanosomes, the amyloid matrix serves as a platform where eumelanin precursors accumulate at high local concentrations for pigment formation. May prevent pigmentation-associated toxicity by sequestering toxic reaction intermediates of eumelanin biosynthesis pathway.
Примечание	For research use only.

Изображения

Western blot

Western blot analysis was performed using anti-PMEL monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human PMEL (Catalog No: HW380012)
Lane 2: negative control
Bioactivity

Detects recombinant human PMEL (Catalog No: HW380012) in indirect ELISA

Ссылки

Даташит

Mouse Anti-Human PMEL17/ME20M Recombinant Antibody (17A9).pdf

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