

| Número de catálogo | VK081022 |
|---|---|
| Descripción |
Recombinant HSV-2/HHV-2 glycoprotein H/gH, N-His (VK081022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | P89445 |
| Longitud de proteína | Arg49-Pro803 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | Envelope glycoprotein H, gH |
| Fondo | Envelope glycoprotein H is a ~89 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Interaction with host integrins ITGAV/ITGB3 triggers release of cytosolic Ca(2+) and FAK phosphorylation leading to efficient viral entry into host genital tract epithelial cells. 1. Cheshenko, N. et al. (2014) Journal of virology 88, 10026-38. PMID: 24942591 |
| Nota | For research use only |

SDS-PAGE for HSV-2/HHV-2 glycoprotein H/gH Recombinant Protein (N-His)
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