

| Каталожный номер | VK081022 |
|---|---|
| Описание |
Recombinant HSV-2/HHV-2 glycoprotein H/gH, N-His (VK081022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Система экспрессии | E. coli |
| Номер доступа | P89445 |
| Длина белка | Arg49-Pro803 |
| Применения | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Виды | Human herpesvirus 2 (HHV-2) (Human herpes simplex virus 2) (HSV-2) |
| Характер | Recombinant |
| Уровень эндотоксинов | Please contact with the lab for this information. |
| Чистота | >90% as determined by SDS-PAGE. |
| Форма | Lyophilized |
| Буфер хранения | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Пожалуйста, обратитесь к конкретной информации о буфере в печатной версии даташита или в индивидуальном сертификате качества (COA) для партии. |
| Реконституция | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Доставка | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Устойчивость и хранение | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Альтернативные названия | Envelope glycoprotein H, gH |
| Фон | Envelope glycoprotein H is a ~89 kDa protein. The heterodimer glycoprotein H-glycoprotein L is required for the fusion of viral and plasma membranes leading to virus entry into the host cell. Following initial binding to host receptor, membrane fusion is mediated by the fusion machinery composed of gB and the heterodimer gH/gL. May also be involved in the fusion between the virion envelope and the outer nuclear membrane during virion morphogenesis. Interaction with host integrins ITGAV/ITGB3 triggers release of cytosolic Ca(2+) and FAK phosphorylation leading to efficient viral entry into host genital tract epithelial cells. 1. Cheshenko, N. et al. (2014) Journal of virology 88, 10026-38. PMID: 24942591 |
| Примечание | For research use only |

SDS-PAGE for HSV-2/HHV-2 glycoprotein H/gH Recombinant Protein (N-His)
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