

| Numéro de catalogue | VK646061 |
|---|---|
| Description |
Recombinant HTNV/KHFV Glycoprotein N/Gn/G1, C-His (VK646061) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Système d'expression | Mammalian cells |
| Numéro d'accès | P08668 |
| Longueur de protéine | Leu19-Glu371 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | Envelopment polyprotein, GP, Gc, Glycoprotein C, Glycoprotein G1, Glycoprotein G2, Glycoprotein N, Glycoprotein precursor, Gn, M polyprotein |
| Contexte | Envelopment polyprotein is a ~126 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. May also bind to host C1QBP for virus entry into the host cell. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome. 1. Raymond, T. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 1163-8. PMID: 15657120 2. Mou, DL. et al. (2006) Biochemical and biophysical research communications 339, 611-7. PMID: 16310165 3. Müller, A. et al. (2019) Virus research 267, 36-40. PMID: 31054291 4. Jin, M. et al. (2002) Virology 294, 60-9. PMID: 11886265 5. Choi, Y. et al. (2008) Virology 381, 178-83. PMID: 18834607 6. Wang, K. et al. (2019) Cell reports 27, 2075-2091.e5. PMID: 31091447 |
| Note | For research use only |




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