Anti-Hantaan virus/HTNV Glycoprotein N/Gn Recombinant Antibody (SAA2516) (VK646043)

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Overview

Catalog No.

VK646043

Description

Anti-Hantaan virus/HTNV Glycoprotein N/Gn Antibody (SAA2516) [SAA2516] (VK646043) is a human monoclonal antibody detecting Glycoprotein N in ELISA, Neutralization.

Species reactivity

Hantaan virus (Korean hemorrhagic fever virus)

Applications

ELISA, Neutralization

Host species

Human

Isotype

IgG1, lambda

Clone ID

SAA2516

Clonality

Monoclonal

Target

Envelopment polyprotein, Glycoprotein G1, Glycoprotein N

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P08668

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Envelopment polyprotein (Glycoprotein N/Gn) is a ~126 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. May also bind to host C1QBP for virus entry into the host cell. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome.

1. Raymond, T. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 1163-8. PMID: 15657120

2. Mou, DL. et al. (2006) Biochemical and biophysical research communications 339, 611-7. PMID: 16310165

3. Müller, A. et al. (2019) Virus research 267, 36-40. PMID: 31054291

4. Jin, M. et al. (2002) Virology 294, 60-9. PMID: 11886265

5. Choi, Y. et al. (2008) Virology 381, 178-83. PMID: 18834607

6. Wang, K. et al. (2019) Cell reports 27, 2075-2091.e5. PMID: 31091447

Note

For research use only

Images

SDS-PAGE

SDS-PAGE for Anti-Hantaan virus/HTNV Glycoprotein N/Gn Antibody (SAA2516)

References

Datasheet

Anti-Hantaan virus/HTNV Glycoprotein N/Gn Recombinant Antibody (SAA2516).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Hantaan virus/HTNV Glycoprotein N/Gn Recombinant Antibody (SAA2516) (VK646043)

Overview

Images

References

Datasheet

SDS

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