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HTNV Glycoprotein Gn Recombinant Protein (C-His) (VK646061)

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概要
カタログ番号VK646061
説明
Recombinant HTNV/KHFV Glycoprotein N/Gn/G1, C-His (VK646061) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●High Purity — >90% as determined by SDS-PAGE.
発現システムMammalian cells
アクセッション番号P08668
タンパク質長Leu19-Glu371
アプリケーションELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV)
性質 Recombinant
エンドトキシンレベル Please contact with the lab for this information.
純度 >90% as determined by SDS-PAGE.
形態 Lyophilized
保存バッファー Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。

再構成 Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送 In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名Envelopment polyprotein, GP, Gc, Glycoprotein C, Glycoprotein G1, Glycoprotein G2, Glycoprotein N, Glycoprotein precursor, Gn, M polyprotein
背景

Envelopment polyprotein is a ~126 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. May also bind to host C1QBP for virus entry into the host cell. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome.

1. Raymond, T. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 1163-8. PMID: 15657120
2. Mou, DL. et al. (2006) Biochemical and biophysical research communications 339, 611-7. PMID: 16310165
3. Müller, A. et al. (2019) Virus research 267, 36-40. PMID: 31054291
4. Jin, M. et al. (2002) Virology 294, 60-9. PMID: 11886265
5. Choi, Y. et al. (2008) Virology 381, 178-83. PMID: 18834607
6. Wang, K. et al. (2019) Cell reports 27, 2075-2091.e5. PMID: 31091447
注意事項 For research use only
イメージ
参考文献
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
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Stock Solution
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Working Solution
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