Human ADAMTS4 Recombinant Protein (N-GST & C-His) (HF893022)

Name: Human ADAMTS4 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HF893022
Price: 211 USD
Availability: InStock

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1mg

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概要
イメージ
参考文献
データシート
SDS

概要

カタログ番号	HF893022
説明	Recombinant Human ADAMTS4 Protein, N-GST & C-His (HF893022) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
発現システム	E. coli
アクセッション番号	O75173
タンパク質長	Phe213-Pro439
アプリケーション	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
種	Homo sapiens (Human)
性質	Recombinant
エンドトキシンレベル	Please contact with the lab for this information.
純度	>90% as determined by SDS-PAGE.
予測分子量	52.60 kDa
形態	Lyophilized
保存バッファー	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。
再構成	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
発送	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
安定性と保存	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
別名	A disintegrin and metalloproteinase with thrombospondin motifs 4, ADAM-TS 4, ADAM-TS4, ADAMTS-4, ADAMTS4, ADMP-1, Aggrecanase-1, EC:3.4.24.82, KIAA0688
背景	A disintegrin and metalloproteinase with thrombospondin motifs 4 is a ~90 kDa protein. Cleaves aggrecan, a cartilage proteoglycan, at the '392-Glu-\|-Ala-393' site and may be involved in its turnover. Also cleaves COMP. May play an important role in the destruction of aggrecan in arthritic diseases. Could be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. 1. Tortorella, MD. et al. (1999) Science (New York, N.Y.) 284, 1664-6. PMID: 10356395 2. Tortorella, M. et al. (2000) The Journal of biological chemistry 275, 25791-7. PMID: 10827174 3. de Groot, R. et al. (2025) Matrix biology : journal of the International Society for Matrix Biology 135, 106-124. PMID: 39672391
注意事項	For research use only