

| Número de catálogo | HY486012 |
|---|---|
| Descripción |
Recombinant Human ADRB1 Protein, N-His-KSI (HY486012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| Sistema de expresión | E. coli |
| Número de acceso | P08588 |
| Longitud de proteína | Gly2-Gln55&His197-Arg222 |
| Aplicaciones | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Especies | Homo sapiens (Human) |
| Naturaleza | Recombinant |
| Nivel de endotoxinas | Please contact with the lab for this information. |
| Pureza | >90% as determined by SDS-PAGE. |
| Peso molecular predicho | 24.22 kDa |
| Forma | Lyophilized |
| Buffer de almacenamiento | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote. |
| Reconstitución | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Envío | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Estabilidad y almacenamiento | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Nombres alternativos | ADRB1, ADRB1R, B1AR, Beta-1 adrenergic receptor, Beta-1 adrenoceptor, Beta-1 adrenoreceptor |
| Fondo | Beta-1 adrenergic receptor is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes. 1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248 2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161 3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775 4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660 5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857 6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867 7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062 |
| Nota | For research use only |

SDS-PAGE for Human ADRB1 Recombinant Protein (N-His-KSI)




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