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Human beta-1 Adrenergic R/ADRB1 Recombinant Protein (N-His-KSI) (HY486012)

Human beta-1 Adrenergic R/ADRB1 Recombinant Protein (N-His-KSI)
Human beta-1 Adrenergic R/ADRB1 Recombinant Protein (N-His-KSI)
Precio(USD):
Especificación:
  • 50ug
  • 100ug
  • 1mg
Número:
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Vista general
Número de catálogoHY486012
Descripción
Recombinant Human ADRB1 Protein, N-His-KSI (HY486012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
Sistema de expresiónE. coli
Número de accesoP08588
Longitud de proteínaGly2-Gln55&His197-Arg222
AplicacionesELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
EspeciesHomo sapiens (Human)
Naturaleza Recombinant
Nivel de endotoxinas Please contact with the lab for this information.
Pureza >90% as determined by SDS-PAGE.
Peso molecular predicho 24.22 kDa
Forma Lyophilized
Buffer de almacenamiento Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.

Reconstitución Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativosADRB1, ADRB1R, B1AR, Beta-1 adrenergic receptor, Beta-1 adrenoceptor, Beta-1 adrenoreceptor
Fondo

Beta-1 adrenergic receptor is a ~51 kDa protein. G protein-coupled receptor for catecholamines that couples to G(s) proteins to activate adenylate cyclase and cAMP-dependent pathway. Binds epinephrine and norepinephrine with approximately equal affinity. Mediates the activation of Ras via binding with cAMP-dependent RAPGEF2. As part of the sympathetic nervous system, plays a role in the physiologic regulation of cardiac functions such as stimulation of cardiomyocyte contraction. Also delivers proapoptotic signals in cardiomyocytes.

1. Mason, DA. et al. (1999) The Journal of biological chemistry 274, 12670-4. PMID: 10212248
2. Pak, Y. et al. (2002) Molecular and cellular biology 22, 7942-52. PMID: 12391161
3. He, J. et al. (2004) The Journal of biological chemistry 279, 50190-6. PMID: 15358775
4. Xu, X. et al. (2021) Cell research 31, 569-579. PMID: 33093660
5. Börjesson, M. et al. (2000) European heart journal 21, 1853-8. PMID: 11052857
6. Ranade, K. et al. (2002) American journal of human genetics 70, 935-42. PMID: 11854867
7. Shi, G. et al. (2019) Neuron 103, 1044-1055.e7. PMID: 31473062
Nota For research use only
Imágenes
  • Human beta-1 Adrenergic R/ADRB1 Recombinant Protein (N-His-KSI)

    SDS-PAGE

    SDS-PAGE for Human ADRB1 Recombinant Protein (N-His-KSI)

Referencias
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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