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| カタログ番号 | HP433011 |
|---|---|
| 説明 |
Recombinant Human ARTN/Artemin Protein, N-Fc (HP433011) expressed in Mammalian Cells, spanning Ala108-Gly220. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | Mammalian cells |
| アクセッション番号 | Q5T4W7 |
| タンパク質長 | Ala108-Gly220 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 39.80 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | ARTN, Artemin, EVN, Enovin, Neublastin |
| 背景 | Artemin is a ~22 kDa protein. Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. 1. Masure, S. et al. (1999) European journal of biochemistry 266, 892-902. PMID: 10583383 2. Baloh, RH. et al. (1998) Neuron 21, 1291-302. PMID: 9883723 3. Li, J. et al. (2019) eLife 8. PMID: 31535977 |
| 注意事項 | For research use only |
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