

| Numéro de catalogue | HX204022 |
|---|---|
| Description |
Recombinant Human CACNA1B Protein, N-His (HX204022) expressed in E. coli, spanning Gly1722-Gln1875. Purity: >90% by SDS-PAGE.
Highlights
|
| Système d'expression | E. coli |
| Numéro d'accès | Q00975 |
| Longueur de protéine | Gly1722-Gln1875 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Espèces | Homo sapiens (Human) |
| Nature | Recombinant |
| Niveau d'endotoxines | Please contact with the lab for this information. |
| Pureté | >90% as determined by SDS-PAGE. |
| Masse moléculaire prédite | 19.94 kDa |
| Forme | Lyophilized |
| Tampon de stockage | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Expédition | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stabilité et stockage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Noms alternatifs | BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, Calcium channel, L type, alpha-1 polypeptide isoform 5, Voltage-dependent N-type calcium channel subunit alpha-1B, Voltage-gated calcium channel subunit alpha Cav2.2 |
| Contexte | Voltage-dependent N-type calcium channel subunit alpha-1B is a ~262 kDa protein. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. 1. Groen, JL. et al. (2015) Human molecular genetics 24, 987-93. PMID: 25296916 |
| Note | For research use only |
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