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Anti-Human CACNA1B Polyclonal Antibody (HX204014)

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Overview
Catalog No.HX204014
Description
Anti-Human CACNA1B Polyclonal Antibody (HX204014) is a rabbit polyclonal antibody detecting CACNA1B. Suitable for Rat, Mouse, and Human.
Highlights
  • ●Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CACNA1B (Gly1722-Gln1875).
Target BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, Calcium channel, L type, alpha-1 polypeptide isoform 5, Voltage-dependent N-type calcium channel subunit alpha-1B, Voltage-gated calcium channel subunit alpha Cav2.2
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q00975
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

Voltage-dependent N-type calcium channel subunit alpha-1B (CACNA1B) is a ~262 kDa protein. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons.

1. Groen, JL. et al. (2015) Human molecular genetics 24, 987-93. PMID: 25296916
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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Anti-Human CACNA1B Polyclonal Antibody

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