Human CACNA1B Recombinant Protein (N-His) (HX204022)

Name: Human CACNA1B Recombinant Protein (N-His)
Brand: abinScience
SKU: HX204022
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	HX204022
Description	Recombinant Human CACNA1B Protein, N-His (HX204022) expressed in E. coli, spanning Gly1722-Gln1875. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q00975
Protein length	Gly1722-Gln1875
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Homo sapiens (Human)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	19.94 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	BIII, Brain calcium channel III, CACH5, CACNA1B, CACNL1A5, Calcium channel, L type, alpha-1 polypeptide isoform 5, Voltage-dependent N-type calcium channel subunit alpha-1B, Voltage-gated calcium channel subunit alpha Cav2.2
Background	Voltage-dependent N-type calcium channel subunit alpha-1B is a ~262 kDa protein. Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This alpha-1B subunit gives rise to N-type calcium currents. N-type calcium channels belong to the 'high-voltage activated' (HVA) group. They are involved in pain signaling. Calcium channels containing alpha-1B subunit may play a role in directed migration of immature neurons. 1. Groen, JL. et al. (2015) Human molecular genetics 24, 987-93. PMID: 25296916
Note	For research use only

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Datasheet

Human CACNA1B Recombinant Protein (N-His).pdf

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Human CACNA1B Recombinant Protein (N-His) (HX204022)

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