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| カタログ番号 | HW730012 |
|---|---|
| 説明 |
Recombinant Human CCT5 Protein, N-His (HW730012) expressed in E. coli, spanning Met1-Glu541. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | P48643 |
| タンパク質長 | Met1-Glu541 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 61.83 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CCT-epsilon, CCT5, CCTE, Chaperonin containing T-complex polypeptide 1 subunit 5, EC:3.6.1.-, KIAA0098, T-complex protein 1 subunit epsilon, TCP-1-epsilon |
| 背景 | T-complex protein 1 subunit epsilon is a ~59 kDa protein. Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of actin, tubulin and other proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. 1. Freund, A. et al. (2014) Cell 159, 1389-403. PMID: 25467444 2. Gestaut, D. et al. (2022) Cell 185, 4770-4787.e20. PMID: 36493755 3. Kelly, JJ. et al. (2022) Nature structural & molecular biology 29, 420-429. PMID: 35449234 4. Liu, C. et al. (2023) Communications biology 6, 531. PMID: 37193829 5. Seo, S. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 1488-93. PMID: 20080638 |
| 注意事項 | For research use only |
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