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| カタログ番号 | HV781012 |
|---|---|
| 説明 |
Recombinant Human CD264/TNFRSF10D/TRAIL-R4 Protein, N-His (HV781012) expressed in E. coli, spanning Glu81-His211. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | E. coli |
| アクセッション番号 | Q9UBN6 |
| タンパク質長 | Glu81-His211 |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 16.21 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CD264, DCR2, DcR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TNFRSF10D, TRAIL receptor 4, TRAIL receptor with a truncated death domain, TRAIL-R4, TRAILR4, TRUNDD, Tumor necrosis factor receptor superfamily member 10D |
| 背景 | Tumor necrosis factor receptor superfamily member 10D is a ~41 kDa protein. Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway. 1. Degli-Esposti, MA. et al. (1997) Immunity 7, 813-20. PMID: 9430226 2. Pan, G. et al. (1998) FEBS letters 424, 41-5. PMID: 9537512 3. Marsters, SA. et al. (1997) Current biology : CB 7, 1003-6. PMID: 9382840 |
| 注意事項 | For research use only |
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