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Anti-Human CD264/TNFRSF10D/TRAIL-R4 Recombinant Antibody (SAA1966) (HV781013)

Anti-Human CD264/TNFRSF10D/TRAIL-R4 Recombinant Antibody (SAA1966)
Anti-Human CD264/TNFRSF10D/TRAIL-R4 Recombinant Antibody (SAA1966)
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Overview
Catalog No.HV781013
Species reactivityHuman
ApplicationsELISA
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDSAA1966
Clonality Monoclonal
Target TRAIL-R4, TRAIL receptor 4, DcR2, TRAIL receptor with a truncated death domain, TRUNDD, DCR2, Decoy receptor 2, TNF-related apoptosis-inducing ligand receptor 4, TRAILR4, TNFRSF10D, Tumor necrosis factor receptor superfamily member 10D, CD264
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession Q9UBN6
RRID

Anti-Human CD264/TNFRSF10D/TRAIL-R4 Antibody (SAA1966) (abinScience Cat# HV781013, RRID:AB_3727730)
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Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:2000-1:20000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

Tumor necrosis factor receptor superfamily member 10D (CD264/TNFRSF10D) is a ~41 kDa protein. Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF-kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.

1. Degli-Esposti, MA. et al. (1997) Immunity 7, 813-20. PMID: 9430226
2. Pan, G. et al. (1998) FEBS letters 424, 41-5. PMID: 9537512
3. Marsters, SA. et al. (1997) Current biology : CB 7, 1003-6. PMID: 9382840
Note For research use only.
Images
  • Anti-Human CD264/TNFRSF10D/TRAIL-R4 Recombinant Antibody (SAA1966)

    SDS-PAGE

    SDS-PAGE for Anti-Human CD264/TNFRSF10D/TRAIL-R4 Antibody (SAA1966)

References
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