Human CD53 Recombinant Protein (N-GST & C-His) (HB750012)

Name: Human CD53 Recombinant Protein (N-GST & C-His)
Brand: abinScience
SKU: HB750012
Price: 211 USD
Availability: InStock

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Número de catálogo	HB750012
Descripción	Recombinant Human CD53 Protein, N-GST & C-His (HB750012) expressed in E. coli, spanning Glu107-Asn181. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Sistema de expresión	E. coli
Número de acceso	P19397
Longitud de proteína	Glu107-Asn181
Aplicaciones	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Especies	Homo sapiens (Human)
Naturaleza	Recombinant
Nivel de endotoxinas	Please contact with the lab for this information.
Pureza	>90% as determined by SDS-PAGE.
Peso molecular predicho	36.55 kDa
Forma	Lyophilized
Buffer de almacenamiento	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Consulte la información específica del buffer en la copia impresa del datasheet o en el COA específico del lote.
Reconstitución	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Envío	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Estabilidad y almacenamiento	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nombres alternativos	CD53, Cell surface glycoprotein CD53, Leukocyte surface antigen CD53, MOX44, TSPAN25, Tetraspanin-25, Tspan-25
Fondo	Leukocyte surface antigen CD53 is a ~24 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Plays a role in the activation of monocytes and B-cells. Acts as an essential regulator of B-cell development by promoting interleukin-7 receptor/IL7R signaling. Also promotes, in B-cells, the BCR signaling by recruiting PKC to the plasma membrane in order to phosphorylate its substrates. 1. Zuidscherwoude, M. et al. (2017) Science signaling 10. PMID: 28487417 2. Yang, Y. et al. (2020) The EMBO journal 39, e105246. PMID: 32974937 3. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951 4. Olweus, J. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 707-16. PMID: 8335905
Nota	For research use only

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Referencias

Datasheet

Human CD53 Recombinant Protein (N-GST & C-His).pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

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Working Solution

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