Anti-Human CD53 Recombinant Antibody (SAA1593) (HB750013)

Name: Anti-Human CD53 Recombinant Antibody (SAA1593)
Brand: abinScience
SKU: HB750013
Price: 196 USD
Availability: InStock

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1mg

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HB750013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1593

Clonality

Monoclonal

Target

CD53, Tetraspanin-25, Leukocyte surface antigen CD53, Cell surface glycoprotein CD53, Tspan-25, TSPAN25, MOX44

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P19397

RRID

Anti-Human CD53 Antibody (SAA1593) (abinScience Cat# HB750013, RRID:AB_3727354)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Leukocyte surface antigen CD53 is a ~24 kDa protein. Structural component of specialized membrane microdomains known as tetraspanin-enriched microdomains (TERMs), which act as platforms for receptor clustering and signaling. Participates thereby in diverse biological functions such as cell signal transduction, adhesion, migration and protein trafficking. Plays a role in the activation of monocytes and B-cells. Acts as an essential regulator of B-cell development by promoting interleukin-7 receptor/IL7R signaling. Also promotes, in B-cells, the BCR signaling by recruiting PKC to the plasma membrane in order to phosphorylate its substrates.

1. Zuidscherwoude, M. et al. (2017) Science signaling 10. PMID: 28487417

2. Yang, Y. et al. (2020) The EMBO journal 39, e105246. PMID: 32974937

3. Dunlock, VE. et al. (2022) Cell reports 39, 111006. PMID: 35767951

4. Olweus, J. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 707-16. PMID: 8335905

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human CD53 Antibody (SAA1593)

References

Datasheet

Anti-Human CD53 Recombinant Antibody (SAA1593).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CD53 Recombinant Antibody (SAA1593) (HB750013)

Overview

Images

References

Datasheet

SDS

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