Human LILRA4/CD85g/ILT7 Recombinant Protein (C-Fc) (HX894021)

Name: Human LILRA4/CD85g/ILT7 Recombinant Protein (C-Fc)
Brand: abinScience
SKU: HX894021
Price: 298 USD
Availability: InStock

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Aperçu

Numéro de catalogue	HX894021
Description	Recombinant Human CD85g/LILRA4/ILT7 Protein, C-Fc (HX894021) expressed in Mammalian Cells. Purity: >90% by SDS-PAGE. Highlights ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
Système d'expression	Mammalian cells
Numéro d'accès	P59901
Longueur de protéine	Met1-Asn446(Leu27Pro)
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Espèces	Homo sapiens (Human)
Nature	Recombinant
Niveau d'endotoxines	Please contact with the lab for this information.
Pureté	>90% as determined by SDS-PAGE.
Masse moléculaire prédite	75.58 kDa
Forme	Lyophilized
Tampon de stockage	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Reférez-vous aux informations spécifiques sur le tampon dans la copie papier du datasheet ou dans le COA spécifique au lot.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Expédition	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stabilité et stockage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Noms alternatifs	CD85 antigen-like family member G, CD85g, ILT-7, ILT7, Immunoglobulin-like transcript 7, LILRA4, Leukocyte immunoglobulin-like receptor subfamily A member 4
Contexte	Leukocyte immunoglobulin-like receptor subfamily A member 4 is a ~55 kDa protein. Functions coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G. Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as a negative regulator of TLR7 and TLR9 signaling cascades. Down-regulates interferon production in response to interaction with BST2 on HIV-1 infected cells. Activates a signaling cascade in complex with FCER1G that results in phosphorylation of Src family and Syk kinases and thereby triggers mobilization of intracellular Ca(2+). Does not interfere with the differentiation of plasmacytoid dendritic cells into antigen-presenting cells. 1. Cao, W. et al. (2006) The Journal of experimental medicine 203, 1399-405. PMID: 16735691 2. Cao, W. et al. (2009) The Journal of experimental medicine 206, 1603-14. PMID: 19564354 3. Tavano, B. et al. (2014) PloS one 9, e89414. PMID: 24586760 4. Bego, MG. et al. (2015) PLoS pathogens 11, e1005024. PMID: 26172439
Note	For research use only

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Human LILRA4/CD85g/ILT7 Recombinant Protein (C-Fc).pdf

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