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| カタログ番号 | HV137021 |
|---|---|
| 説明 |
Recombinant Human CD85h/LILRA2 Protein, C-Fc (HV137021) expressed in Mammalian Cells. Purity: >90% by SDS-PAGE.
Highlights
|
| 発現システム | Mammalian cells |
| アクセッション番号 | Q8N149 |
| タンパク質長 | Met1-Asn449(Ser135Leu) |
| アプリケーション | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 種 | Homo sapiens (Human) |
| 性質 | Recombinant |
| エンドトキシンレベル | Please contact with the lab for this information. |
| 純度 | >90% as determined by SDS-PAGE. |
| 予測分子量 | 75.75 kDa |
| 形態 | Lyophilized |
| 保存バッファー | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. データシートのハードコピーまたはロット固有のCOAに記載された具体的なバッファー情報を参照してください。 |
| 再構成 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 発送 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 安定性と保存 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 別名 | CD85 antigen-like family member H, CD85h, ILT-1, ILT1, Immunoglobulin-like transcript 1, LILRA2, LIR-7, LIR7, Leukocyte immunoglobulin-like receptor 7, Leukocyte immunoglobulin-like receptor subfamily A member 2 |
| 背景 | Leukocyte immunoglobulin-like receptor subfamily A member 2 is a ~52 kDa protein. Part of the innate immune responses against microbial infection. Specifically recognizes a set of N-terminally truncated immunoglobulins that are produced via cleavage by proteases from a range of pathogenic bacteria and fungi, including L.pneumophila, M.hyorhinis, S.pneumoniae, S.aureus and C.albicans. Recognizes epitopes that are in part in the variable region of the immunoglobulin light chains, but requires also the constant region for signaling. Binds to a subset of cleaved IgM, IgG3 and IgG4 molecules, but does not bind cleaved IgA1. Binding of N-terminally truncated immunoglobulins mediates activation of neutrophils. 1. Tedla, N. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 1174-9. PMID: 12529506 2. Hirayasu, K. et al. (2016) Nature microbiology 1, 16054. PMID: 27572839 3. Lu, HK. et al. (2012) PloS one 7, e33478. PMID: 22479404 4. Chen, Y. et al. (2009) Journal of molecular biology 386, 841-53. PMID: 19230061 |
| 注意事項 | For research use only |
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