Anti-Human CD85h/LILRA2 Polyclonal Antibody (HV137014)

Name: Anti-Human CD85h/LILRA2 Polyclonal Antibody
Brand: abinScience
SKU: HV137014
Price: 168 USD
Availability: InStock

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Datasheet
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Overview

Catalog No.

HV137014

Description

Anti-Human CD85h/LILRA2 Polyclonal Antibody (HV137014) is a rabbit polyclonal antibody detecting LILRA2 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD85h/LILRA2 (Gly24-Val417).

Target

Leukocyte immunoglobulin-like receptor subfamily A member 2, CD85 antigen-like family member H, Immunoglobulin-like transcript 1, ILT-1, Leukocyte immunoglobulin-like receptor 7, LIR-7, CD85h, LILRA2, ILT1, LIR7

Purification

Purified by antigen affinity column.

Accession

Q8N149

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Leukocyte immunoglobulin-like receptor subfamily A member 2 (CD85h/LILRA2) is a ~52 kDa protein. Part of the innate immune responses against microbial infection. Specifically recognizes a set of N-terminally truncated immunoglobulins that are produced via cleavage by proteases from a range of pathogenic bacteria and fungi, including L.pneumophila, M.hyorhinis, S.pneumoniae, S.aureus and C.albicans. Recognizes epitopes that are in part in the variable region of the immunoglobulin light chains, but requires also the constant region for signaling. Binds to a subset of cleaved IgM, IgG3 and IgG4 molecules, but does not bind cleaved IgA1. Binding of N-terminally truncated immunoglobulins mediates activation of neutrophils.

1. Tedla, N. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 1174-9. PMID: 12529506

2. Hirayasu, K. et al. (2016) Nature microbiology 1, 16054. PMID: 27572839

3. Lu, HK. et al. (2012) PloS one 7, e33478. PMID: 22479404

4. Chen, Y. et al. (2009) Journal of molecular biology 386, 841-53. PMID: 19230061

Note

For research use only.

Images

References

Datasheet

Anti-Human CD85h/LILRA2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human CD85h/LILRA2 Polyclonal Antibody (HV137014)

Overview

Images

References

Datasheet

SDS

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